Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrPC signaling
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چکیده
منابع مشابه
Highlight: self-renewal signaling in stem cells.
A number of ground-breaking studies recently identified sets of nuclear factors that together have the unique ability to ‘reset’ an adult differentiated cell type and to ‘erase’ all previous fate decisions and the transcriptional programs that determine phenotype and function of a differentiated cell (Takahashi et al., 2007; Wernig et al., 2007; Yu et al., 2007). As a result, ‘reprogrammed’ cel...
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It is well known that the Dpp signal transducer Mad is activated by phosphorylation at its carboxy-terminus. The role of phosphorylation on other regions of Mad is not as well understood. Here we report that the phosphorylation of Mad in the linker region by the Wg antagonist Zw3 (homolog of vertebrate Gsk3-β) regulates the development of sensory organs in the anterior-dorsal quadrant of the wi...
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ژورنال
عنوان ژورنال: Theranostics
سال: 2019
ISSN: 1838-7640
DOI: 10.7150/thno.35619